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Insights

Placebell©™ Predicts Placebo Response in Initial Study in Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, as it affects 1-2 per 1000 of the population at any time(1). Although it is primarily…

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Education

Where Does Placebo Response in Clinical Trials Come From? 6 Influences

Placebo response is a major source of noise in trial data analysis, muddying the results and making it more difficult to detect true treatment effect. We know…

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Insights

The Importance of Patient Psychology in Health and Clinical Research

When we think about patient characteristics that influence health, disease, and clinical research, we tend to think about things like vital statistics, medical history and genetic makeup…

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Education

Clinical Trial Statistical Analysis: How to Minimize Noise

The main objective of most clinical trials is to evaluate efficacy and safety of an experimental treatment. To do this, statisticians compare the response of the drug-treated…

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Insights

The placebo response in drug development. Part 4: Irritable Bowel Disease

As in many other diseases (e.g. pain, osteoarthritis, rheumatoid arthritis, Parkinson’s Disease, etc ), patients participating in clinical trials for IBD treatments may experience a pronounced placebo…

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Multimedia

Predict placebo response using patient psychology to increase trial power

Advanced methods like AI and machine learning are uniquely poised to help scientists uncover the full spectrum of patient placebo responsiveness in a clinical trial. Learn more about this approach by attending our webinar, which explains how a solution like Placebell©™ leverages a time-tested predictive…

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Education

How to Increase Clinical Study Power with Covariate Adjustment

Adjustment for covariates helps clinical trial statisticians demonstrate differences in drug effect between groups of people. In this blog, we discuss what this means and how it…

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