Library

Publication

Predicting the Placebo response in OA to Improve the Precision of the Treatment Effect Estimation

Scientific Poster presented on April 2021 at the Osteoarthritis Research Society International Meeting. Purpose In osteoarthritis (OA) randomized…

Type: Scientific Poster
Authors: Samuel Branders1; Jamie Dananberg2; Frederic Clermont1; Ben Xie2; Benjamin Hsu2; J. Visich2; Akbar Khan2; Lauren Masaki2; Alvaro Pereira1 1-Tools4Patient, Mont-Saint-Guibert, Belgium 2-Unity Biotechnology, Inc., South San Francisco, CA
Conference: Osteoarthritis Research Society International (OARSI)
Read More
Publication

Can Daily Self-Assessment Induce A Learning Effect Mitigating Pain Evaluation Error In Randomized Clinical Trials?

Scientific Poster presented on April 2021 at the Osteoarthritis Research Society International Meeting. Purpose Questionnaires assessing  patients’ pain level…

Type: Scientific Poster
Authors: Arthur Ooghe, M.E.; Samuel Branders, Ph.D.; Alvaro Pereira, Ph.D.
Conference: Osteoarthritis Research Society International (OARSI)
Read More
Publication

Modelling of PNP and OA Placebo Response: Working towards a unique model of the placebo response in chronic pain?

In analgesia randomized clinical trials (RCTs), the magnitude and the variability of the placebo response negatively impacts the…

Type: Scientific Poster
Authors: Samuel Branders, PhD ; Alvaro Pereira, PhD ; Erica Smith, PhD ; Dominique Demolle, PhD.
Conference: CNS Clinical Trials and Methodology (ISCTM)
Read More
Publication

Identification Of Peripheral Neuropathic Pain Sensory Phenotypes Based On Specific Combinations Of Symptoms Identified With The NPSI (Neuropathic Pain Symptom Inventory)

One way to better personalized the treatment of peripheral neuropathic pain (PNP) would be to identify specific sensory…

Type: Scientific Presentation
Authors: Didier Bouhassira(1), Samuel Banders(2), Nadine Attal(1), Dominique Demolle(2) and Alvaro Pereira(2). 1- Inserm 987, Ambroise Pare Hospital, 92100 Boulogne-Billancourt, France 2- Tools4Patient, 50 rue de Bordeaux, boîte 17, 6040 Jumet, Belgium
Conference: European Pain Federation (EFIC)
Read More
Publication

Leveraging Historical Data For High-dimensional Covariate-adaptive Randomization, A Machine Learning Approach.

There is a continuous growth in data collected in clinical trials. Many of those patient’s characteristics are potential…

Type: Scientific Presentation
Authors: Samuel Branders, PhD; Guillaume Bernard, PhD; Alvaro Pereira, PhD
Conference: Promoting Statistical Insight Conference
Read More
Publication

Correcting For The Individual Patient Regression To The Mean Effect

Often, the primary endpoint of RCTs is defined as a change from baseline of a continuous outcome. In…

Type: Scientific Poster
Authors: Samuel Branders, PhD; Guillaume Bernard, PhD; Alvaro Pereira, PhD
Conference: American Society for Clinical Pharmacology and Therapeutics
Read More