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Publication

MODELING THE EXPECTATIONS FOR IMPROVEMENT IN OSTEOARTHRITIS TRIALS TO ENHANCE MANAGEMENT STRATEGIES 

Objective: The expectations of improvement among subjects participating in a Randomized Controlled Trials (RCT) are one of the…

Type: Poster Abstract
Authors: Arthur Ooghe; Jerome Paul, PhD; Alvaro Pereira, PhD
Conference: OARSI 2024
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Publication

Using aggregated site features computed with the MPsQ to allow a better monitoring of sites in clinical trials

Using aggregated site features computed with the MPsQ to allow a better monitoring of sites in clinical trials…

Type: Scientific Poster
Authors: Arthur Ooghe, Samuel Branders, Jérôme Paul, Dominique Demolle, Alvaro Pereira
Conference: CNS Summit 2023
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Publication

Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials

Cognivia team members contribute critical elements to a recent paper published in Innovations in Clinical Neuroscience. Cognivia co-authored a…

Type: White Paper
Authors:
Conference: ISCTM
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Publication

Accounting for the high reduction of power due to floor effect in design of randomised controlled trials

Purpose  Outcomes in Randomized Controlled Trials (RCT) are often computed as changes from baseline of finite scales (e.g.,…

Type: Scientific Poster
Authors: A. Ooghe, S. Branders, J. Paul, A. Pereira Tools4Patient s.a. (dba Cognivia)
Conference: OARSI 2023
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Publication

Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials

The amount of data collected from patients involved in clinical trials is continuously growing. All baseline patient characteristics…

Type: Scientific Publication
Authors: Samuel Branders, Alvaro Pereira, Guillaume Bernard, Marie Ernst, Jamie Danenberg, Adelin Albert
Conference: Statistical Methods in Medical Research Journal
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Publication

Impact of excluding highly variable pain subjects on the treatment estimation

The baseline pain variability (BPV) has often been presented as positively correlating with the placebo response (PR) and…

Type: Scientific Poster
Authors: Arthur Ooghe, Samuel Branders, Alvaro Pereira
Conference: CNS Summit
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