Library

Insights

Placebell©™ Predicts Placebo Response in Initial Study in Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, as it affects 1-2 per 1000 of the population at any time(1). Although it is primarily…

Read More
Insights

Placebell©™ Predicts Placebo Response in Initial Study in Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, as it affects 1-2 per 1000 of the population at any time(1). Although it is primarily…

Read More
Education

Placebo Effect vs. Placebo Response: Is There A Difference?

Placebo effect and placebo response are often used interchangeably – despite being two different phenomena. In this blog, we highlight the differences—and why it matters.   Placebos are an important…

Read More
Education

Mitigating the Placebo Response in Phase II & III Clinical Trials

Phase II and III trial failure due to unexpectedly large placebo response rates is still all too common. In this blog, we explain what this means and…

Read More
Insights

Prediction of placebo response in Osteoarthritis improves estimation of the treatment effect: Impact on drug development

Placebell©™ can be used in OA and similar diseases in which efficacy is characterized using patient-reported outcomes to reduce the interference of the placebo effect and improve…

Read More
Education

Understanding the Placebo Effect: Increasing Clinical Trial Success

Placebos are used in randomized, placebo-controlled controlled trials, in which one group (or more) receives the active treatment and the other group receives the placebo control. This…

Read More
Insights

The placebo response – a phenomenon related to the placebo group or to the individual patient?

Historically, interpretation of clinical trials relies on “assay sensitivity”, or the sensitivity to detect clinically meaningful differences between endpoints measured in the group of patients given active…

Read More